Plan Scoring for RTOG 0126

The scoring criteria for this protocol assumes that 3DCRT plans will use a cone down (optional) after the first 31 fractions of treatment.  If this is not done the scoring criteria for IMRT plans should be used.

Target Scoring-Arm1-3DCRT
No Variation		Minor Variation	Major Variation
98 % of  PTV1 is at, or above 55.8 Gy, and		95% of PTV1 is at, or above 55.8 Gy and	Failure to achieve either No Variation or Minor Variation
98 % of PTV2 and 100 % of CTV2 is at or above 70.2 Gy, and		95 % of PTV2 and 100 % of CTV2 is at or above 70.2 Gy, and
Maxdose2%PTV2 <75.1 Gy		Maxdose2%PTV2<77.2 Gy
Target Scoring-Arm2-3DCRT
No Variation		Minor Variation		Major Variation
98 % of  PTV1 is at, or above 55.8 Gy, and		95% of PTV1 is at, or above 55.8 Gy and		Failure to achieve either No Variation or Minor Variation
98 % of PTV2 and 100% of CTV2 is at or above 79.2 Gy, and		95 % of PTV2 and 100 % of CTV2 is at or above 79.2 Gy, and
Maxdose2%PTV2 <84.7 Gy		Maxdose2%PTV2 <87.1 Gy
Target Scoring-Arm1-IMRT
No Variation	Minor Variation			Major Variation
98 % of PTV is at, or above 70.2 Gy, and	95% of PTV is at, or above 70.2 Gy and			Failure to achieve either No Variation or Minor Variation
100% of CTV is at or above 70.2 Gy, and	100% of CTV is at or above 70.2 Gy, and
Maxdose2%PTV <75.1 Gy	Maxdose2%PTV<77.2 Gy
Target Scoring-Arm2-IMRT
No Variation		Minor Variation		Major Variation
98 % of PTV is at, or above 79.2 Gy, and		95% of PTV is at, or above 79.2 Gy and		Failure to achieve either No Variation or Minor Variation
100% of CTV is at or above 79.2 Gy, and		100% of CTV is at or above 79.2 Gy, and
Maxdose2%PTV <84.7 Gy		Maxdose2%PTV <87.1 Gy

Organs at Risk (OAR)

Based upon a review of patient dosimetry on dose level 3 of RTOG 94-06, the following normal tissue limits are guidelines and should be followed:

Normal organ limit†	No more than 15% volume receives dose that exceeds	No more than 25% volume receives dose that exceeds	No more than 35% volume receives dose that exceeds	No more than 50% volume receives dose that exceeds
Bladder Constraint	80 Gy	75 Gy	70 Gy	65 Gy
Rectum Constraint	75 Gy	70 Gy	65 Gy	60 Gy

Revised 5/14/2004.